Propranolol for infantile haemangiomas: a review.
نویسندگان
چکیده
Infantile haemangiomas are the most common benign tumour of infancy. However the majority are self-resolving and only a small minority of cases require treatment, with various different medications being used in the past. Over the last few years, propranolol, a non-selective β-blocker, has become a popular and successful treatment for infantile haemangiomas. However, further research on its safety is needed if it is going to be used more frequently. This article summarises the current literature on propranolol for haemangioma treatment with emphasis on its toxicity and adverse event profile.
منابع مشابه
Use of propranolol in infantile haemangiomas: report of five cases and review of the literature.
Infantile haemangiomas are common benign tumours that do not require treatment unless they cause significant functional impairment or disfigurement. We report our experience with the off-label use of propranolol in 5 children with haemangiomas and review the relevant literature.
متن کاملPropranolol therapy for infantile haemangiomas: review of the literature.
OBJECTIVES Haemangiomas are the most common tumors of infancy affecting approximately 1 in 10 children. Unlike other tumors, haemangiomas enter an involution phase, during which they usually regress over the next several months to years. Sometimes intervention is required due to proliferative growth which is complicated by ulceration, bleeding, persistent aesthetic deformity or infection. MET...
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OBJECTIVE To assess the safety and efficacy of systemic propranolol for the treatment of complicated infantile haemangiomas. DESIGN Retrospective review of case notes of paediatric patients treated with propranolol for complicated infantile haemangiomas. SETTING Tertiary care children's hospital. PATIENTS All paediatric patients with complicated infantile haemangiomas who commenced treatm...
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Cutaneous infantile haemangiomas affect approximately 1 in 10 children. They tend to follow a natural course of rapid proliferation during the first year of life and subsequently regress over 5-10 years. Most haemangiomas are non-problematic, but a few become problematic, through ocular, airway or functional impairment, or ulceration. Oral propranolol therapy has been observed to inhibit the pr...
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Capillary haemangiomas are benign lesions that may occur anywhere on the skin, may grow rapidly in the first two years of life and may impair vital organs. Propranolol has been recently discovered to shrink these lesions effectively. We report the first such patient treated in Malta with this drug.
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 96 9 شماره
صفحات -
تاریخ انتشار 2011